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Recent Advances in Quantitative Synthetic-Polymer Mass Spectrometry at NIST

Published

Author(s)

William E. Wallace, Charles M. Guttman

Abstract

Commensurate with NIST s mission to advance the state of quantitative measurement science we have worked to develop a method to determine absolute molecular mass distribution of synthetic polymers by mass spectrometry. Work has centered on using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) on low-mass, narrow-polydispersity polystyrene. We are developing a Taylor s expansion approach that may be used to guide the experimentalist in finding the correct measurement conditions to assure quantitation. Along with this we are developing an uncertainty budget (for both Type A and Type B uncertainties) so the experimenter can ascertain the level of confidence in the final quantitative measure of molecular mass distribution.
Proceedings Title
ASMS Conference on Mass Spectrometry and Allied Topics | 52nd | Proceedings of the 52nd ASMS Conference on Mass Spectrometry and Allied Topics | American Society for Mass Spectrometry (ASMS)
Volume
33(1)
Conference Dates
May 23-27, 2004
Conference Location
Nashville, TN
Conference Title
ASMS Conference on Mass Spectrometry

Keywords

mass spectrometry, molecular mass distribution, polymer quantitation

Citation

Wallace, W. and Guttman, C. (2004), Recent Advances in Quantitative Synthetic-Polymer Mass Spectrometry at NIST, ASMS Conference on Mass Spectrometry and Allied Topics | 52nd | Proceedings of the 52nd ASMS Conference on Mass Spectrometry and Allied Topics | American Society for Mass Spectrometry (ASMS), Nashville, TN, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852391 (Accessed June 25, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created January 1, 2004, Updated February 19, 2017