Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Properties of Calcium Phosphate Cement with Chondroitin Sulfate

Published

Author(s)

S Hirayama, Francis W. Wang, Shozo Takagi, T Ikemi

Abstract

The objectives of this study were to evaluate the setting times, mechanical strengths and hydroxyapatite (HA) conversion of polymer-modified self-hardening calcium phosphate cements (CPCs) that were prepared with chondroitin sulfate solutions of various concentrations as the liquid components. The setting times of all in the CSA group were significantly different (p < 0.05) from those of the control. But the setting times of all in the CSA group were not significantly different even though the HA conversion of the CSA group decreased with the increasing mass fraction of CSA solution. The diametral tensile strength (DTS) and compressive strength (CS) of specimens made from CSA solutions with mass fractions of (15 and 25) % were not significantly different (p > 0.05) from those for the control group. However, The DTS and CS of specimens made from CSA solutions with mass fractions of (5 and 50) % were significantly lower (p < 0.05) than those for the control group. These results suggested that it is worthwhile for the improvement of CPC that are made from CSA solutions with mass fractions between (15 and 25) %.
Proceedings Title
The 6th World Biometerials Congress
Conference Dates
May 15-20, 2000
Conference Location
Undefined
Conference Title
World Biomaterials Congress

Keywords

calcium phosphate cement, Condroitin sulfate, glycosaminoglycan, hydroxyapatite, mechanical strength

Citation

Hirayama, S. , Wang, F. , Takagi, S. and Ikemi, T. (2021), Properties of Calcium Phosphate Cement with Chondroitin Sulfate, The 6th World Biometerials Congress, Undefined (Accessed December 13, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created October 12, 2021