Properties of Calcium Phosphate Cement with Chondroitin Sulfate

Published

October 12, 2021

Author(s)

S Hirayama, Francis W. Wang, Shozo Takagi, T Ikemi

Abstract

The objectives of this study were to evaluate the setting times, mechanical strengths and hydroxyapatite (HA) conversion of polymer-modified self-hardening calcium phosphate cements (CPCs) that were prepared with chondroitin sulfate solutions of various concentrations as the liquid components. The setting times of all in the CSA group were significantly different (p < 0.05) from those of the control. But the setting times of all in the CSA group were not significantly different even though the HA conversion of the CSA group decreased with the increasing mass fraction of CSA solution. The diametral tensile strength (DTS) and compressive strength (CS) of specimens made from CSA solutions with mass fractions of (15 and 25) % were not significantly different (p > 0.05) from those for the control group. However, The DTS and CS of specimens made from CSA solutions with mass fractions of (5 and 50) % were significantly lower (p < 0.05) than those for the control group. These results suggested that it is worthwhile for the improvement of CPC that are made from CSA solutions with mass fractions between (15 and 25) %.

Proceedings Title

The 6th World Biometerials Congress

Conference Dates

May 15-20, 2000

Conference Location

Undefined

Conference Title

World Biomaterials Congress

Pub Type

Conferences

Keywords

calcium phosphate cement, Condroitin sulfate, glycosaminoglycan, hydroxyapatite, mechanical strength

Citation

Hirayama, S. , Wang, F. , Takagi, S. and Ikemi, T. (2021), Properties of Calcium Phosphate Cement with Chondroitin Sulfate, The 6th World Biometerials Congress, Undefined (Accessed June 8, 2025)