Petersen, E.
, Barrios, A.
, Henry, T.
, Johnson, M.
, Koelmans, A.
, Montoro Bustos, A.
, Matheson, J.
, Roesslein, M.
, Zhao, J.
and Xing, B.
(2022),
Potential artifacts and control experiments in toxicity tests of nanoplastic and microplastic particles, Environmental Science & Technology, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=934051
(Accessed April 26, 2024)
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Potential artifacts and control experiments in toxicity tests of nanoplastic and microplastic particles
Published
Author(s)
, , Theodore Henry, , Albert Koelmans, , Joanna Matheson, Matthias Roesslein, Jian Zhao, Baoshan Xing
Abstract
To fully understand the potential ecological and human health risks from nanoplastics and microplastics (NMPs) in the environment, it is critical to make accurate measurements. Similar to past research on the toxicology of engineered nanomaterials, a broad range of measurement artifacts and biases are possible when testing their potential toxicity. Therefore, control measurements are needed to assess whether artifacts have occurred, and revisions to the protocol may be needed to eliminate or reduce the artifacts. In this paper, we comprehensively review and suggest control experiments to identify measurement artifacts and biases that can occur while performing NMP toxicity experiments. Incorporation of these control experiments can reduce the likelihood of false positive and false negative results and help elucidate the potential ecological and human health risks of NMPs.Citation
Environmental Science & Technology
Pub Type
Journals
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Citation
Created October 14, 2022, Updated November 29, 2022