Population data for 94 identity SNPs in four U.S. population groups

Published

September 23, 2022

Author(s)

Kevin Kiesler, Lisa Borsuk, Becky Steffen, Katherine Gettings, Peter Vallone

Abstract

The U.S. National Institute of Standards and Technology (NIST) sequenced 1036 human DNA samples from four United States population groups (African American, Asian, Hispanic, and Caucasian) using the ForenSeq DNA Signature Prep Kit with Primer Mix B (DPMB) on a MiSeq FGx instrument. In addition to STR markers, DPMB includes amplification primers for single nucleotide polymorphisms (SNPs) used for individual identification (iiSNPs, n = 94), ancestry inference (aiSNPs, n = 56), and phenotype prediction (piSNPs, n = 22). Resulting sequencing coverage information was interpreted for the 94 iiSNP markers. Here we present performance characteristics of the ForenSeq DNA Signature Prep Kit in the population studied.

Citation

Forensic Science International: Genetics Supplement Series

Volume

8

Pub Type

Journals

Download Paper

https://doi.org/10.1016/j.fsigss.2022.09.003

Local Download

Keywords

single nucleotide polymorphism (SNP), identity informative SNP, DNA sequencing

Citation

Kiesler, K. , Borsuk, L. , Steffen, B. , Gettings, K. and Vallone, P. (2022), Population data for 94 identity SNPs in four U.S. population groups, Forensic Science International: Genetics Supplement Series, [online], https://doi.org/10.1016/j.fsigss.2022.09.003, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=935528 (Accessed October 9, 2025)