Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Population data for 94 identity SNPs in four U.S. population groups

Published

Author(s)

Kevin Kiesler, Lisa Borsuk, Becky Steffen, Katherine Gettings, Peter Vallone

Abstract

The U.S. National Institute of Standards and Technology (NIST) sequenced 1036 human DNA samples from four United States population groups (African American, Asian, Hispanic, and Caucasian) using the ForenSeq DNA Signature Prep Kit with Primer Mix B (DPMB) on a MiSeq FGx instrument. In addition to STR markers, DPMB includes amplification primers for single nucleotide polymorphisms (SNPs) used for individual identification (iiSNPs, n = 94), ancestry inference (aiSNPs, n = 56), and phenotype prediction (piSNPs, n = 22). Resulting sequencing coverage information was interpreted for the 94 iiSNP markers. Here we present performance characteristics of the ForenSeq DNA Signature Prep Kit in the population studied.
Citation
Forensic Science International: Genetics Supplement Series
Volume
8

Keywords

single nucleotide polymorphism (SNP), identity informative SNP, DNA sequencing

Citation

Kiesler, K. , Borsuk, L. , Steffen, B. , Gettings, K. and Vallone, P. (2022), Population data for 94 identity SNPs in four U.S. population groups, Forensic Science International: Genetics Supplement Series, [online], https://doi.org/10.1016/j.fsigss.2022.09.003, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=935528 (Accessed April 25, 2024)
Created September 23, 2022, Updated February 9, 2023