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PEPR: Pipeline for Evaluating Prokaryotic References

Published

Author(s)

Nathanael D. Olson, Justin M. Zook, Daniel V. Samarov, Scott A. Jackson, Marc L. Salit

Abstract

The rapid adoption of microbial whole genome sequencing in public health, clinical testing, and forensic labo-ratories requires the use of validated and well characterized measurement processes. Reference materials thatare well characterized and homogeneous and stable can be used to evaluate measurement processes and helpto establish confidence in results from a measurement process. With the variety microbial genome sequenc-ing applications, platforms and genomic diversity, there is a need for a wide variety of application-specificgenomic materials for use in method validation. Here we present a Pipeline for Evaluating Prokaryotic Ref- erences, “PEPR”, a common bioinformatic pipeline for use in characterizing prokaryotic genomic materials.
Citation
Analytical and Bioanalytical Chemistry
Issue
408

Keywords

microbiology, genomics, bioinformatics

Citation

Olson, N. , Zook, J. , Samarov, D. , Jackson, S. and Salit, M. (2016), PEPR: Pipeline for Evaluating Prokaryotic References, Analytical and Bioanalytical Chemistry, [online], https://doi.org/10.1007/s00216-015-9299-5 (Accessed July 3, 2022)
Created April 1, 2016, Updated November 10, 2018