Skip to main content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Patterned Surface Energy in Elastomeric Molds as a Generalized Approach to Polymer Particle Fabrication



Samuel D. Oberdick, Gary Zabow


We present a generic fabrication scheme to produce polymer microparticles with engineerable, complex shapes. The polymer particles are made from a polyethylene-glycol based hydrogel using a polydimethylsiloxane (PDMS) based molding technique. A simple surface treatment is used to pattern the surface energy of the PDMS molds, engendering the recessed molds with a higher surface energy than the PDMS surface. The contrast in surface energy causes hydrogel precursor to wet only the inside of the molds, creating isolated particles after curing with UV light. This eliminates the formation of an interconnecting “scum” layer and allows for fabrication of well-defined, independent particles. A simple strategy for releasing the particles is also presented.
ACS Applied Polymer Materials


microparticles, microfabrication, hydrogel, PDMS
Created January 2, 2020, Updated March 15, 2020