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Optical Manipulation and Fusion of Liposomes as Microreactors

Published

Author(s)

S Kulin, N Kishore, Kristian Helmerson, Laurie E. Locascio

Abstract

We present an all optical method to manipulate and fuse giant liposomes, typically 10 nm in diameter. Optical tweezers are used to trap two individual liposomes, which are then brought into contact. A single pulse of ultraviolet laser light focused on the adjoining membranes induces the fusion between the liposomes. As a consequence the chemical reagents encapsulated in the two liposomes mix and a chemical reaction takes place.
Citation
Langmuir
Volume
19
Issue
No. 20

Keywords

liposomes, optical tweezers

Citation

Kulin, S. , Kishore, N. , Helmerson, K. and Locascio, L. (2003), Optical Manipulation and Fusion of Liposomes as Microreactors, Langmuir (Accessed March 28, 2024)
Created September 1, 2003, Updated February 17, 2017