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NIST Fatty Acid Quality Assurance Program 2017 Final Report



Bruce A. Benner Jr., Jacolin A. Murray


At the request of the National Institutes of Health’s (NIH’s) Office of Dietary Supplements (ODS) and in conjunction with the Centers for Disease Control and Prevention (CDC), in 2017 the National Institute of Standards and Technology (NIST) conducted the fourth Fatty Acid Quality Assurance Program (FAQAP) interlaboratory study of fatty acid (FA) concentrations in human serum. This 2017 FAQAP study included measurements of free FAs (extraction and measurement prior to acid/base hydrolysis) and total FAs (measurement after acid/base hydrolysis). Participants were requested to analyze SRM 1950 Metabolites in Human Plasma as a control, three “unknown” sera, and a free fatty acid (FFA) solution. Participants measuring fatty acid methyl ester (FAME) derivatives of FAs were asked to analyze a FAME solution. The results from this fourth exercise are reported along with a summary of the analytical methods used by the fourteen participating laboratories.
NIST Interagency/Internal Report (NISTIR) - 8273
Report Number


free fatty acids, total fatty acids, serum


Benner, B. and Murray, J. (2019), NIST Fatty Acid Quality Assurance Program 2017 Final Report, NIST Interagency/Internal Report (NISTIR), National Institute of Standards and Technology, Gaithersburg, MD, [online], (Accessed February 27, 2024)
Created October 1, 2019