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NAA Characterization of the New Bovine Liver SRM



Rolf L. Zeisler, W. D. James, Elizabeth A. Mackey, Rabia Oflaz, Robert R. Greenberg


The National Institute of Standards and Technology (NIST) is preparing a freeze-dried powdered bovine liver tissue Standard Reference Material (SRM) to replace SRM1577b Bovine Liver as the stock of this material was exhausted during 2006. Like the original SRM 1577 issued in 1972, this renewal focuses on the key elements for diagnostic, nutritional, and toxicological measurements that are important to medical, veterinary, and environmental sciences investigations. To preserve the natural elemental composition, the tissues were collected and prepared under strict protocols at the Texas A&M University College of Veterinary Medicine from 31 freshly slaughtered steers. The preparation resulted in 1840 units of the proposed SRM 1577c. NIST's approach for value assignment included extensive characterization by neutron activation analysis (NAA). Difficulties in the determination of some elements present at very low-levels were overcome by use of radiochemical separations. Twenty-one elements were characterized in SRM 1577c by NAA. The previous materials, SRM 1577 and 1577b served as control
Journal of Radioanalytical and Nuclear Chemistry


activation analysis, Bovine liver, certification, instrumental neutron activation analysis, radiochemical neutron, standard reference material, trace elements, value assignment


Zeisler, R. , James, W. , Mackey, E. , Oflaz, R. and Greenberg, R. (2008), NAA Characterization of the New Bovine Liver SRM, Journal of Radioanalytical and Nuclear Chemistry (Accessed April 15, 2024)
Created October 16, 2008