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Microfluidic Transport and Sensing of Functionalized Superparamagnetic Beads with Integrated Spin-Valves

Published

Author(s)

Wendy R. Altman, John M. Moreland, Stephen E. Russek, Victor M. Bright

Abstract

This work describes a novel microfluidic platform to trap, release, transport, and detect superparamagnetic beads (SPBs) with magnetic spin-valves (SVs). This new technique for simultaneous SPB manipulation and detection was demonstrated on a linear array of bistable 1 υm × 8 υm bottom-pin SVs (approximately equal}3% GMR) addressed locally with read and write lines. We successfully transported, trapped, and detected a single 2.8 υm diameter SPB. During detection, the SPB was magnetized with an in-plane +9 mT field perpendicular to the SV's easy axis.
Proceedings Title
The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Conference Dates
October 2-6, 2011
Conference Location
Seattle, WA, US

Keywords

Biomanipulation, Spin-valve Sensor, Spin-valve trap, Superparamagnetic bead

Citation

Altman, W. , Moreland, J. , Russek, S. and Bright, V. (2011), Microfluidic Transport and Sensing of Functionalized Superparamagnetic Beads with Integrated Spin-Valves, The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Seattle, WA, US (Accessed May 26, 2024)

Issues

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Created October 1, 2011, Updated October 12, 2021