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Making digital phantoms with spectral and spatial light modulators for quantitative applications of hyperspectral optical medical imaging devices



Bonghwan Chon, fuyuki Tokumasu, Ji Youn Lee, David W. Allen, Joseph P. Rice, Jeeseong Hwang


We present a procedure to generate digital phantoms with a hyperspectral image projector (HIP) consisting of two liquid crystal on silicon (LCoS) spatial light modulators (SLMs). The digital phantoms are 3D image data cubes of the spatial distribution of spectrally resolved abundances of intracellular light-absorbing oxy-hemoglobin molecules in single erythrocytes. Spectrally and spatially resolved image data indistinguishable from the real scene may be used as standards to calibrate image sensors and validate image analysis algorithms for their measurement quality, performance consistency, and inter-laboratory comparisons for quantitative biomedical imaging applications.
SPIE Conference Proceedings


Imaging system, medical optics, microscopy, imaging standard, spatial light modulator
Created March 6, 2015, Updated November 10, 2018