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Limit of detection determination for censored samples.
Published
Author(s)
Andrew L. Rukhin, Daniel V. Samarov
Abstract
The problem of setting the limit of detection is considered for censored samples and heterogeneous errors. After formal definitions of the critical level and of the method detection limit, we introduce simplified maximum likelihood-type estimators. The estimation problem of the truncation parameter and its uncertainty is reviewed. Upper confidence bounds for the limit of detection are derived and some simulation results are given.
Rukhin, A.
and Samarov, D.
(2011),
Limit of detection determination for censored samples., Chemometrics and Intelligent Laboratory Systems, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=906715
(Accessed October 10, 2025)