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Limit of detection determination for censored samples.

Published

Author(s)

Andrew L. Rukhin, Daniel V. Samarov

Abstract

The problem of setting the limit of detection is considered for censored samples and heterogeneous errors. After formal definitions of the critical level and of the method detection limit, we introduce simplified maximum likelihood-type estimators. The estimation problem of the truncation parameter and its uncertainty is reviewed. Upper confidence bounds for the limit of detection are derived and some simulation results are given.
Citation
Chemometrics and Intelligent Laboratory Systems
Volume
105

Keywords

censored sampling, confidence intervals, critical level, decision limit, heteroscedasticity, maximum likelihood estimator, tolerance limits. censored sampling, confidence intervals, critical level, decision limit, heteroscedasticity, maximum likelihood estimator, tolerance limits

Citation

Rukhin, A. and Samarov, D. (2011), Limit of detection determination for censored samples., Chemometrics and Intelligent Laboratory Systems, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=906715 (Accessed May 28, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created January 11, 2011, Updated February 19, 2017