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Intramolecular Structure and Dynamics in Computationally Designed Peptide-Based Polymers Displaying Tunable Chain Stiffness

Published

Author(s)

Nairiti Sinha, Yi Shi, Christopher J. Kloxin, Jeffery G. Saven, Antonio Faraone, Grethe V. Jensen, Darrin J. Pochan

Abstract

Polymers constructed via hybrid physical-covalent assembly of computationally designed peptide coiled coils, or bundlemers, display tunable chain stiffness via control of inter-bundlemer connectivity. Neutron spin echo spectroscopy reveals that rigid rod polymers of bundlemers possess a dynamic decay rate Γ Q2 behavior over the entire accessible probed range of wave vector, Q, whereas the semi-rigid chains with small flexible linkers exhibit distinct bending modes (Γ Q8/3) at intermediate-Q. Identical Γ Q2 behavior at high Q is indicative of similar, local bundlemer dynamics in both polymer systems.
Citation
Physical Review Materials
Volume
5
Issue
9

Keywords

Neutron Spin Echo, Bundlemers, polymers

Citation

Sinha, N. , Shi, Y. , Kloxin, C. , Saven, J. , Faraone, A. , Jensen, G. and Pochan, D. (2021), Intramolecular Structure and Dynamics in Computationally Designed Peptide-Based Polymers Displaying Tunable Chain Stiffness, Physical Review Materials (Accessed May 19, 2024)

Issues

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Created September 6, 2021, Updated September 20, 2022