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Injectable Calcium Phosphate Cement: Effects of Powder-to-Liquid Ratio and Needle Size

Published

Author(s)

Elena F. Burguera, Hockin D. Xu, Limin Sun

Abstract

Calcium phosphate cement (CPC) sets in-situ with intimate contact with neighboring bone and forms apatite with excellent osteoconductivity and bone-replacement capability. The objectives of the present study were: to formulate an injectable tetracalcium phosphate (TTCP)-dicalcium phosphate (DCPD) cement (referred to as CPCD); and to investigate the effects of cement powder/liquid ratio and needle size on injectability. Varying the needle size from 10 gauge (inner diameter = 2.69 mm) to 25 gauge (0.26 mm) had a significant effect on injection. The injection force (mean sd; n = 4) significantly increased from (8 2) N using the 10-gauge needle to (144 17) N using the 21-gauge needle (Tukey s at p of 0.05). Varying the powder/liquid mass ratio from 2 to 4 also had a significant effect on injection. Using the 10-gauge needle, the mass percentage of paste extruded was (95 4) % at powder/liquid of 3; it decreased to (70 12) % at powder/liquid of 3.5 (p
Citation
Biomaterials
Volume
84B

Keywords

bone repari, calcium phosphate cement, injectability, nano apatite strength

Citation

Burguera, E. , Xu, H. and Sun, L. (2007), Injectable Calcium Phosphate Cement: Effects of Powder-to-Liquid Ratio and Needle Size, Biomaterials, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852731 (Accessed April 22, 2024)
Created July 16, 2007, Updated February 19, 2017