The National Institute of Standards and Technology (NIST) performs calibrations that achieve the highest level of measurement quality for the makers and users of precision devices world-wide. The information system that administers these calibrations should be of the same high quality and reliability. The devices that NIST calibrates cover a wide sprectrum, ranging from physcial measurement standards to software algorithms. Such a diverse set of equipment types put a tremendous strain on the development of any supporting software, having to cover a wide variety of extremes. This paper describes the information system used by NIST to support their calibration program. It describes the processes used to design and implement the system along with details of its use by the technical and administrative staff. Although the system was initially designed for a focused calibration program, it has been easily extended for use throughout the entire NIST calibration program. The system is World Wide Web (WWW) based using a Standard Query Language SQL database and the Practical Extraction and Reporting Language (PERL), and therefore not reliant on any particular commercial product.