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IMMOBILIZED ENZYME CATALYZED POLYMERIZATION REACTIONS IN MICROREACTORS

Published

Author(s)

Santanu S. Kundu, Atul Bhangale, William E. Wallace, Kathleen M. Flynn, Richard Gross, Kathryn L. Beers

Abstract

Application of microreactor technologies enable improved safety, selectivity and yield in a range of chemical reactions in addition to new measurement methods that are often faster, cheaper and more accurate than traditional methods. In this study we have considered a model system, Candida antartica Lipase B (CAL B) catalyzed polycaprolactone synthesis from -caprolactone. CAL B was immobilized on polymethyl methacrylate support and was loaded in the microchannel reactors. Raman spectroscopy, Nuclear Magnetic resonance (NMR) and Gel permeation Chromatography (GPC) were used to characterize the reaction products. The monomer conversion in microreactors was faster than that observed in the batch reactors.
Proceedings Title
American Chemical Society Spring 2010 National Meeting
Volume
51
Issue
1
Conference Dates
March 21-25, 2010
Conference Location
San Francisco, CA

Keywords

microreactor, enzyme catalysis, ring opening polymerization

Citation

Kundu, S. , Bhangale, A. , Wallace, W. , Flynn, K. , Gross, R. and Beers, K. (2010), IMMOBILIZED ENZYME CATALYZED POLYMERIZATION REACTIONS IN MICROREACTORS, American Chemical Society Spring 2010 National Meeting , San Francisco, CA, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=904143 (Accessed June 19, 2024)

Issues

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Created January 1, 2010, Updated February 19, 2017