NOTICE: Due to a lapse in annual appropriations, most of this website is not being updated. Learn more.

Form submissions will still be accepted but will not receive responses at this time. Sections of this site for programs using non-appropriated funds (such as NVLAP) or those that are excepted from the shutdown (such as CHIPS and NVD) will continue to be updated.

U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PUBLICATIONS

IMMOBILIZED ENZYME CATALYZED POLYMERIZATION REACTIONS IN MICROREACTORS

Published

Author(s)

Santanu S. Kundu, Atul Bhangale, William E. Wallace, Kathleen M. Flynn, Richard Gross, Kathryn L. Beers

Abstract

Application of microreactor technologies enable improved safety, selectivity and yield in a range of chemical reactions in addition to new measurement methods that are often faster, cheaper and more accurate than traditional methods. In this study we have considered a model system, Candida antartica Lipase B (CAL B) catalyzed polycaprolactone synthesis from -caprolactone. CAL B was immobilized on polymethyl methacrylate support and was loaded in the microchannel reactors. Raman spectroscopy, Nuclear Magnetic resonance (NMR) and Gel permeation Chromatography (GPC) were used to characterize the reaction products. The monomer conversion in microreactors was faster than that observed in the batch reactors.
Proceedings Title
American Chemical Society Spring 2010 National Meeting
Volume
51
Issue
1
Conference Dates
March 21-25, 2010
Conference Location
San Francisco, CA
Pub Type
Conferences

Download Paper

Local Download

Keywords

microreactor, enzyme catalysis, ring opening polymerization
Biomaterials, Chemical engineering and processing, Materials, Materials characterization and Polymers

Citation

Kundu, S. , Bhangale, A. , Wallace, W. , Flynn, K. , Gross, R. and Beers, K. (2010), IMMOBILIZED ENZYME CATALYZED POLYMERIZATION REACTIONS IN MICROREACTORS, American Chemical Society Spring 2010 National Meeting , San Francisco, CA, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=904143 (Accessed October 7, 2025)

Issues

If you have any questions about this publication or are having problems accessing it, please contact [email protected].

Created January 1, 2010, Updated February 19, 2017
Was this page helpful?