An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Identification of a Highly-Specific Hydroxyapatite-Binding Peptide Using Phage Display
Published
Author(s)
Matthew Becker, Marc Roy, Scott K. Stanley, Eric J. Amis
Abstract
Using a phage display approach we have identified a peptide sequence SVSVGMKPSPRP that selectively recognizes HA over amorphous calcium phosphate. Exploitation of the recognition properties of such peptidic species to specific polymorphs deposited during mineralization processes and in hydroxyapatite (HA)-derivatized composites may be useful in future studies for monitoring the progression of mineralization and potentially cell differentiation in situ as opposed to destructive endpoint measurements.
Becker, M.
, Roy, M.
, Stanley, S.
and Amis, E.
(2008),
Identification of a Highly-Specific Hydroxyapatite-Binding Peptide Using Phage Display, Advanced Materials
(Accessed June 5, 2023)