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PUBLICATIONS

Hydroxyl radical is a significant player in oxidative DNA damage in vivo.

Published

Author(s)

Miral M. Dizdar, Barry Halliwell, Amitav Adhikary, Michael Dingfelder

Abstract

Recent publications have suggested that oxidative DNA damage mediated by hydroxyl radical (.OH) is unimportant in vivo, and that carbonate anion radical (CO3.-) plays the key role. We examine these claims and summarize the evidence that OH does play a key role as an important member of the reactive oxygen species (ROS) in vivo.
Citation
Chemical Society Reviews
Pub Type
Journals

Download Paper

https://doi.org/10.1039/D1CS00044F
Local Download

Keywords

hydroxyl radical, DNA damage, oxidative stress
Health

Citation

Dizdar, M. , Halliwell, B. , Adhikary, A. and Dingfelder, M. (2021), Hydroxyl radical is a significant player in oxidative DNA damage in vivo., Chemical Society Reviews, [online], https://doi.org/10.1039/D1CS00044F, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=931588 (Accessed October 22, 2025)

Issues

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Created June 15, 2021, Updated October 14, 2021
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