Hydroxyl radical is a significant player in oxidative DNA damage in vivo.
Miral M. Dizdar, Barry Halliwell, Amitav Adhikary, Michael Dingfelder
Recent publications have suggested that oxidative DNA damage mediated by hydroxyl radical (.OH) is unimportant in vivo, and that carbonate anion radical (CO3.-) plays the key role. We examine these claims and summarize the evidence that OH does play a key role as an important member of the reactive oxygen species (ROS) in vivo.
, Halliwell, B.
, Adhikary, A.
and Dingfelder, M.
Hydroxyl radical is a significant player in oxidative DNA damage in vivo., Chemical Society Reviews, [online], https://doi.org/10.1039/D1CS00044F, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=931588
(Accessed October 26, 2021)