NOTICE: Due to a lapse in annual appropriations, most of this website is not being updated. Learn more.
Form submissions will still be accepted but will not receive responses at this time. Sections of this site for programs using non-appropriated funds (such as NVLAP) or those that are excepted from the shutdown (such as CHIPS and NVD) will continue to be updated.
An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
High Sensitivity CARS Microscopy With Two Tightly SynChronized Picosecond Lasers
Published
Author(s)
J Potman, D J. Jones, J X. Cheng, X. Xie, Jun Ye
Abstract
We demonstrate a significant improvement in signal-to-noise ratio recovered from coherent anti-Stokes Raman scattering (CARS) spectroscopy/microscopy, using two tightly synchronized picosecond Ti: sapphire lasers. A temporal jitter between the pulse trains form the two independent commercial lasers is reduced from a few ps to 21 fs, observed over several hours. We present detailed statistical analysis along with enhanced CARS vibrational images of living cells and polymer beads.
Potman, J.
, Jones, D.
, Cheng, J.
, Xie, X.
and Ye, J.
(2021),
High Sensitivity CARS Microscopy With Two Tightly SynChronized Picosecond Lasers, Optics Letters
(Accessed October 11, 2025)