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High Sensitivity CARS Microscopy With Two Tightly SynChronized Picosecond Lasers

Published

Author(s)

J Potman, D J. Jones, J X. Cheng, X. Xie, Jun Ye

Abstract

We demonstrate a significant improvement in signal-to-noise ratio recovered from coherent anti-Stokes Raman scattering (CARS) spectroscopy/microscopy, using two tightly synchronized picosecond Ti: sapphire lasers. A temporal jitter between the pulse trains form the two independent commercial lasers is reduced from a few ps to 21 fs, observed over several hours. We present detailed statistical analysis along with enhanced CARS vibrational images of living cells and polymer beads.
Citation
Optics Letters

Keywords

biological imaging, coherent anti-Stokes Raman scattering (C, spectroscopy/microscopy

Citation

Potman, J. , Jones, D. , Cheng, J. , Xie, X. and Ye, J. (2021), High Sensitivity CARS Microscopy With Two Tightly SynChronized Picosecond Lasers, Optics Letters (Accessed February 24, 2024)
Created October 12, 2021