Potman, J.
, Jones, D.
, Cheng, J.
, Xie, X.
and Ye, J.
(2021),
High Sensitivity CARS Microscopy With Two Tightly SynChronized Picosecond Lasers, Optics Letters
(Accessed May 21, 2025)
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High Sensitivity CARS Microscopy With Two Tightly SynChronized Picosecond Lasers
Published
Author(s)
, D J. Jones, J X. Cheng, X. Xie,
Abstract
We demonstrate a significant improvement in signal-to-noise ratio recovered from coherent anti-Stokes Raman scattering (CARS) spectroscopy/microscopy, using two tightly synchronized picosecond Ti: sapphire lasers. A temporal jitter between the pulse trains form the two independent commercial lasers is reduced from a few ps to 21 fs, observed over several hours. We present detailed statistical analysis along with enhanced CARS vibrational images of living cells and polymer beads.Citation
Optics Letters
Pub Type
Journals
Keywords
biological imaging, coherent anti-Stokes Raman scattering (C, spectroscopy/microscopy
Citation
Issues
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Created October 12, 2021