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Federal perspective on critical research issues in nanoEHS



Janet Carter, Sri Nadadur, Rhema Bjorkland, William Boyes, Chuck Geraci, Vincent A. Hackley, John Howard, Alan Kennedy, Igor Linkov, Joanna Matheson, Holly Mortensen, Custudio Muinga, Elijah Petersen, Nora Savage, Stacey Standridge, Trey Thomas, Benjamin Trump


This article discusses critical issues and opportunities going forward in nanotechnology environmental, health, and safety (nanoEHS) research from the perspective of Federal Government agency participants in the U.S. National Nanotechnology Initiative (NNI) interagency Nanotechnology Environmental and Health Implications (NEHI) Working Group. NEHI is responsible for coordination of Federal science agency nanoEHS research. As participants in NEHI, we examine these critical issues from an integrated, transdisciplinary perspective, noting examples of impactful research efforts that are advancing knowledge in these areas. Major themes identified include detection, measurement, and characterization of real-world nanomaterial exposures, understanding the biological transformation of nanomaterials and their potential (eco)toxicological implications, understanding the landscape of nanotechnology-enabled products in commerce, and advancing the EHS knowledge infrastructure related to nanomaterials and nanotechnology. Significant investments in nanoEHS research over two decades have led to establishment of a unique and diverse multidisciplinary, multisector community of practice. These investments must be leveraged and adapted not only to future nanotechnology, but also to use as a model for accelerating acquisition of safe and reliable risk information for tomorrow's emerging technologies for a more sustainable and competitive world.
Environmental Science: Nano


nanotechnology, environment, health, safety, standards, reference materials, risk assessment, NNI


Carter, J. , Nadadur, S. , Bjorkland, R. , Boyes, W. , Geraci, C. , Hackley, V. , Howard, J. , Kennedy, A. , Linkov, I. , Matheson, J. , Mortensen, H. , Muinga, C. , Petersen, E. , Savage, N. , Standridge, S. , Thomas, T. and Trump, B. (2023), Federal perspective on critical research issues in nanoEHS, Environmental Science: Nano, [online],, (Accessed May 24, 2024)


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Created August 31, 2023, Updated September 11, 2023