Evaluation of Low-Contrast Detectability of Iterative Reconstruction across Multiple Institutions, CT Scanner Manufacturers, and Radiation Exposure Levels
Adele P. Peskin, Ganesh Saiprasad, James J. Filliben, Alden A. Dima
Purpose: To evaluate the impact of Iterative Reconstruction (IR) compared with Filtered Back Projection (FBP) using low-contrast objects in phantom images across vendors and exposure levels. Materials and Methods: Randomized repeat scans of the Gammex 464 American College of Radiology (ACR) CT Accreditation Phantom (Module 2, Low-contrast) were performed for multiple radiation exposures, vendors and vendor IR algorithms. Eleven volunteers were presented with a total of 900 images using a custom designed Graphical User Interface (GUI) to perform a task created specifically for this reader study. Results were analyzed using Exploratory Data Analysis (EDA) (1) statistical graphics (2) methodology. Results: Statistical analysis concluded that across all three vendors (blinded as A, B, and C) and across all exposure levels, the Correct Classification Rate (CCR) was higher for IR than FBP (p
, Saiprasad, G.
, Filliben, J.
and Dima, A.
Evaluation of Low-Contrast Detectability of Iterative Reconstruction across Multiple Institutions, CT Scanner Manufacturers, and Radiation Exposure Levels, Radiology, [online], https://doi.org/10.1148/radiol.2015141260
(Accessed December 2, 2023)