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Effect of 3D Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells

Published

Author(s)

Carl G. Simon Jr., Girish Kumar, Marian F. Young

Abstract

Structural properties of polymeric scaffolds for tissue engineering play a key role in directing osteogenesis. These properties depend on the chemical nature and the fabrication process of biomaterial. There are many protocols for fabricating scaffolds for bone tissue engineering applications which afford control over scaffold topography. In addition, much work has demonstrated that cell differentiation is sensitive to topography at sizes ranging from nano- to micro- to macroscale. Thus, we have investigated the effect of different scaffold topographies on differentiation of human bone marrow stromal cells (hBMSCs).
Conference Dates
April 13-16, 2011
Conference Location
Orlando, FL
Conference Title
Society for Biomaterials

Keywords

polymer scaffold, stem cell, osteogenesis, nanofiber

Citation

Simon, C. , Kumar, G. and Young, M. (2011), Effect of 3D Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells, Society for Biomaterials, Orlando, FL (Accessed April 22, 2024)
Created April 24, 2011, Updated February 19, 2017