Zhang, K.
, Washburn, B.
and Simon Jr., C.
(2005),
Cytotoxicity Evaluation of Three Dimensionally Ordered Macroporous Sol-gel Bioactive Glass (3DOM-BG) Particles, Society for Biomaterials, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852451
(Accessed October 5, 2024)
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Cytotoxicity Evaluation of Three Dimensionally Ordered Macroporous Sol-gel Bioactive Glass (3DOM-BG) Particles
Published
Author(s)
K J. Zhang, ,
Abstract
Sol-gel bioactive glasses (BGs) are a type of third generation biomaterial (i.e., materials that are both bioactive and bioresorbable). Recently, sol-gel bioactive glasses with three dimensionally ordered macroporous structures (3DOM-BGs) were developed by a sol-gel process combined with a colloidal crystal templating method. 3DOM-BGs have been proven to be bioactive (as represented by the bone-like apatite formation) and fully resorbable (as represented by the complete conversion of 3DOM-BG to apatite) in an acellular in vitro model (simulated body fluid). This study continues the research of 3DOM-BGs with an emphasis on their in vitro cellular responses. Wst-1 assay, phase contrast and fluorescence microscopy showed that 3DOM-BG particles are non-cytotoxic and in vitro compatible with osteoblasts.Citation
Society for Biomaterials
Volume
26 No. 22
Pub Type
Journals
Download Paper
Keywords
bioglass, biomaterial, calcium phosphate, cell adhesion, cytoxicity
Citation
Issues
If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.
Created July 31, 2005, Updated October 12, 2021