Controlled transport of superparamagnetic beads with spin-valves

Published

October 7, 2011

Author(s)

Wendy R. Altman, John M. Moreland, Stephen E. Russek, Bruce W. Han, Victor M. Bright

Abstract

Trapping, release, and transport of individual or ensembles of 2.8 υm superparamagnetic beads functionalized with streptavidin were demonstrated using an addressable and non-volatile array of spin-valve (SV) traps integrated into a microfluidic channel. The linear array consists of two staggered lines of 1 υm × 8 υm SVs toggled "on" or "off" using 10 ms 150 mΑ or -100 mΑ current pulses, respectively. The bead is trapped when the SV is on and released or ignored when the SV is off. This "switchable permanent magnet" offers a low power alternative to other precision microfluidic transport devices.

Citation

Small

Volume

99

Issue

14

Pub Type

Journals

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DOI Link

Keywords

superparamagnetic beads, spin-valve (SV) traps, switchable permanent magnet, microfluidic transport devices, addressable and non-volatile array

Citation

Altman, W. , Moreland, J. , Russek, S. , Han, B. and Bright, V. (2011), Controlled transport of superparamagnetic beads with spin-valves, Small, [online], https://doi.org/10.1063/1.3645615 (Accessed April 16, 2024)