Gordon A. Shaw, David J. Ross, Steven E. Fick, Wyatt N. Vreeland
We propose a new technique, contactless differential conductivity detection (CDCD,) to improve the detection limit of contactless conductivity detection for capillary and microchannel electrophoresis. By exploiting a 3-electrode differential configuration, CDCD greatly reduces the dominant noise source in contactless conductivity detection: temperature fluctuations within the measurement system. This will be a particularly important feature for high-conductivity samples, which are most susceptible to thermal noise. The reduced sensitivity of CDCD to temperature fluctuations and its potential suitability for low-power operation will also make this an excellent candidate for field-portable and point-of-application uses where optical detection strategies may be more difficult to implement.
, Ross, D.
, Fick, S.
and Vreeland, W.
Contactless Differential Conductivity Detection, Proceedings of microTAS 2008, San Diego, CA, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=824689
(Accessed December 6, 2023)