Comparison of Molecular Weight Moments from MALDI-TOF-MS With Other Absolute Methods on a Standard Reference Polymer
Kathleen M. Flynn, William R. Blair, P O. Danis
Matrix Assisted Laser Desorption Ionization (MALDI) Time of Flight (TOF) Mass Spectrometry was used to study the molecular weight distribution (MWD) and the number of α-methyl styrene (α-MeSty) repeat units in SRM 1487, a narrow MWD poly (methyl methacrylate) standard reference material of about 6300 g/mole which was initiated with α-MeSty. It was found that each PMMA polymer chain had from zero to seven alpha-MeStys per chain. The MWD of the polymer chains containing a fixed number of α-MeStys was obtained. The MWD, Mw and the average number of α-MeSty at a given molecular weight from MALDI TOF MS compare well with those obtained from more traditional methods like ultracentrifugation and Size Exclusion Chromatography (SEC).
, Blair, W.
and Danis, P.
Comparison of Molecular Weight Moments from MALDI-TOF-MS With Other Absolute Methods on a Standard Reference Polymer, ANTEC Conference Proceedings
(Accessed June 5, 2023)