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Combinatorial Methods to Access Cellular Response to Bis-GMA/TEGDMA Vinyl Conversion Levels

Published

Author(s)

Nancy J. Lin, L A. Bailey, N Washburn

Abstract

To facilitate the evaluation of dental composites, high throughput methods to fabricate dental resins with varying conversion levels were developed. Resins of 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy) phenyl]propane (Bis-GMA) and triethylene glycol dimethacrylate (TEGDMA) were fabricated to contain one-dimensional gradients in carbon-carbon double bond conversion. Final conversion profiles ranged from 46 % to 67 % conversion. Cellular viability was evaluated as a function of resin conversion, with viability decreasing as conversion decreased. This high-throughput method for developing samples with conversion gradients could be applied to other dental resins or photopolymerized materials.
Proceedings Title
Proceedings of the Society for Biomaterials 2005 Annual Meeting
Conference Dates
April 27-30, 2005
Conference Location
Memphis, TN
Conference Title
Society for Biomaterials Annual Meeting

Keywords

Combinatorial Methods, Conversion, Dental Resin, Viability

Citation

Lin, N. , Bailey, L. and Washburn, N. (2005), Combinatorial Methods to Access Cellular Response to Bis-GMA/TEGDMA Vinyl Conversion Levels, Proceedings of the Society for Biomaterials 2005 Annual Meeting, Memphis, TN, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852433 (Accessed February 29, 2024)
Created April 1, 2005, Updated February 19, 2017