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CHALLENGES AND SUCCESS FOR NEUTRON ACTIVATION ANALYSIS PROCEDURES IN VALUE ASSIGNMENT OF ANIMAL SERUM AND BOVINE LIVER STANDARD REFERENCE MATERIALS

Published

Author(s)

Rolf L. Zeisler, Robert R. Greenberg, Elizabeth A. Mackey, Karen E. Murphy, Rabia Oflaz, Bryan E. Tomlin

Abstract

Analyses for value assignment in the renewal SRMs 1598a Animal Serum and SRM 1577c Bovine Liver included extensive characterization by neutron ac-tivation analysis (NAA). For the determination of Al, V, Mn, and Cu the inter-fering reaction 31P(n,alpha)28Al and the Compton background in the gamma-spectrometry were minimized by use of pre-irradiation chemical separations. Radiochemical separations to reduce the Bremstrahlung and Compton back-ground were employed for the determination of Ag, As, Cd, Cr, Cu, Mo, Sb, and Se. The use of (anti-) coincidence gamma-ray spectrometry systems sig-nificantly improved the signal to background ratio and facilitated the instru-mental determination of Ag, Cr, and Hg. These procedures complemented the conventional instrumental NAA (INAA) of samples prepared in linear poly-ethylene and additional samples sealed in vials made from ultra-pure synthetic quartz. The previous materials, SRMs 1598, 1577, and 1577b, were analyzed together with the new materials for quality control.
Citation
Journal of Radioanalytical and Nuclear Chemistry
Volume
281

Keywords

Animal Serum SRM, Bovine Liver SRM, Chelex separation, mass spectrometry, neutron activation analysis, value assignment
Created June 12, 2009, Updated February 17, 2017