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Calcium Phosphate Cement With Non-Rigidity and Strength Durability for Periodontal Bone Repair



Hockin D. Xu, Shozo Takagi, Limin Sun, L A. Hussain, Laurence C. Chow, William F. Guthrie, James H. Yen


Background. The need for biomaterials to treat periodontal osseous defects has increased as the world population ages. The objective of the present study was to develop a self-hardening, resorbable, and mech/anically strong calcium phosphate cement (CPC) in a non-rigid form that can provide the needed compliance for tooth motion in periodontal bone repair. Methods. Tetracalcium phosphate, dicalcium phosphate anhydrous, and biopolymer chitosan were used to develop a strong and non-rigid CPC composite. A powder:liquid ratio of 2:1 was used, compared to 1:1 for a non-rigid CPC developed previously, which served as the control. Specimens were immersed in a physiological solution for different times and characterized by using a flexural test, scanning electron microscopy (SEM), and powder X-ray diffraction (XRD). Statistical Analysis. Two-way and one-way ANOVA and Tukey s multiple comparison test (p = 0.05) were performed to detect significant effects of material composition and immersion time. Results. After 28 d of immersion, the new cement A had a flexural strength (mean sd; n = 6) of (5.2 1.0) MPa, higher than (1.8 1.5) MPa for the control (p
Journal of the American Dental Association


calcium phosphate cement, nano hydroxyapatite, non-rigid, periodontal bone repair, strain, strength


Xu, H. , Takagi, S. , Sun, L. , Hussain, L. , Chow, L. , Guthrie, W. and Yen, J. (2006), Calcium Phosphate Cement With Non-Rigidity and Strength Durability for Periodontal Bone Repair, Journal of the American Dental Association, [online], (Accessed May 30, 2024)


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Created August 1, 2006, Updated February 17, 2017