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Broadband Coherent Anti-Stokes Raman Scattering



Charles H. Camp


Broadband coherent anti-Stokes Raman scattering (BCARS) microspectroscopy is a unique label-free imaging modality that provides detailed chemical information at each pixel. In minutes, this technique captures a “hyperspectral” cube that co-registers microscopic spatial features with chemical signatures, sensitive to molecular content and structure. This technique can delve into the molecular inner workings of cells and tissues, illuminating, for example, health and disease, cell function and state. In this work, I will provide an overview of BCARS technology, from the basic theory to future directions and provide demonstrations of imaging of histological section of mouse tissue.
Imaging and Dermatology
Publisher Info
Elsevier, Biomedical Research, Waltham, MA


Broadband coherent anti-Stokes Raman scattering, Nonlinear microscopy, Raman spectroscopy, Coherent Raman Imaging, coherent anti-Stokes Raman scattering, label-free microscopy, microspectroscopy
Created August 11, 2016, Updated November 10, 2018