Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Adhesive bonding to dentin improved by polymerizable cyclodextrin derivatives



Rafael L. Bowen, Gary E. Schumacher, Anthony A. Giuseppetti, Kathleen M. Flynn, Charles M. Guttman, Clifton M. Carey


Objectives. Determine bonding characteristics of a hydrophilic monomer formulation containing PCDs (Polymerizable Cyclodextrin Derivatives). The hypothesis was that a formulation containing hydrophilic cross-linking diluent comonomers and PCD molecules could form strong adhesive bonds to dentin. Methods. PCDs were formulated with sorbitol dimethacrylate, methacrylic acid and phenylbis(2,4,6-trimethylbenzoyl)phosphine oxide photoinitiator (Formulation 1). The same formulation without PCDs isolated the effects of the PCDs (Formulation 2). A commercial self-etching bonding system was a comparative control (Formulation 3). Ground mid-coronal dentin was etched with 37 % H3PO4 for 15 s and rinsed with distilled H2O for 10 s. Formulations were applied to the moist dentin and light-cured 10 s. A packable composite was then applied through irises and light-cured 60 s. Teeth were stored in water for 24 h before bonds were tested in a shearing orientation. One-way ANOVA was performed on the data. Results. The average (n = 6) values of Shear Bond Strength (SBS), defined as loads at fracture divided by the 4 mm diameter iris areas, were: Formulation: 1 2 3 SBS in MPa (SD): 24.6 (5.4) 13.2 (3.7) 17.4 (4.0) SBS of Formulation 1 was higher (p<0.05) than that of Formulation 2, evincing that the PCDs led to improved bonding, and was also higher than that of Formulation 3 (p<0.05). Significance. These preliminary results are in accordance with the hypothesis that formulations containing PCDs can form strong adhesive bonds to hydrated dentin surfaces. Further improvements in bonding of resins and composites to hydrated biological tissues such as dentin by means of optimized PCD formulations are anticipated.
Journal of Research (NIST JRES) -


Dental Materials, Adhesive Bonding, Polymerizable Cyclodextrin Derivatives (PCDs), Hydrophilic Cross-linking Comonomers, Shear Bond Strength


Bowen, R. , Schumacher, G. , Giuseppetti, A. , Flynn, K. , Guttman, C. and Carey, C. (2009), Adhesive bonding to dentin improved by polymerizable cyclodextrin derivatives, Journal of Research (NIST JRES), National Institute of Standards and Technology, Gaithersburg, MD, [online], (Accessed July 20, 2024)


If you have any questions about this publication or are having problems accessing it, please contact

Created January 5, 2009, Updated February 19, 2017