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Activity standard and calibrations for 227Th with ingrowing progeny

Published

Author(s)

Denis E. Bergeron, Jeffrey T. Cessna, Brittany Broder, Leticia Pibida, Ryan P. Fitzgerald, Morgan DiGiorgio, Elisa Napoli, Brian E. Zimmerman

Abstract

Thorium-227 was separated from its progeny and standardized for activity by the triple-to-double coincidence ratio (TDCR) method of liquid scintillation counting. Confirmatory liquid scintillation-based measurements were made using efficiency tracing with 3H and live-timed anticoincidence counting (LTAC). The separation time and the efficiency of the separation were confirmed by gamma-ray spectrometry. Calibrations for reentrant pressurized ionization chambers, including commercial radionuclide calibrators, and a well-type NaI(Tl) detector are discussed.
Citation
Applied Radiation and Isotopes
Volume
209

Keywords

Th-227, Ra-223, primary standard, decay chain, progeny ingrowth, dose calibrator, gamma counter, decay data, targeted alpha therapy, precision medicine, administered activity

Citation

Bergeron, D. , Cessna, J. , Broder, B. , Pibida, L. , Fitzgerald, R. , DiGiorgio, M. , Napoli, E. and Zimmerman, B. (2024), Activity standard and calibrations for 227Th with ingrowing progeny, Applied Radiation and Isotopes, [online], https://doi.org/10.1016/j.apradiso.2024.111326, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=957117 (Accessed May 19, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created April 20, 2024, Updated May 14, 2024