3d, Quantitative Image Analysis Of Poly(ε-caprolactone) Scaffolds With Bicontinuous Morphology

Published

April 27, 2004

Author(s)

Joy P. Dunkers, Forrest A. Landis, K Niihara, Hiropshi Jinai

Abstract

It has been shown that scaffold microstructure impacts cell response.1 Determining the relationship between scaffold structure and cellular response facilitates scaffold design. Some descriptors of scaffold morphology thought to be influential are pore volume, pore size distribution, connectivity, curvature, and surface area. In this work, we apply methods developed for 3-dimensional (3D) characterization of polymer blends2 as bicontinuous structures to elucidate microstructural descriptors for a similarly derived poly(ε-caprolactone) (PCL) scaffold. The results here will include pore volume, pore size distribution, and connectivity. Surface curvature, surface area and anisotropy will be discussed in future work.

Conference Dates

April 27-30, 2004

Conference Location

Memphis, TN

Conference Title

Society for Biomaterials
30th Annual Meeting and Exposition

Pub Type

Conferences

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Keywords

scaffolds, pore size distribution, connectivity, curvature, poly(e-caprolactone)

Citation

Dunkers, J. , Landis, F. , Niihara, K. and Jinai, H. (2004), 3d, Quantitative Image Analysis Of Poly(ε-caprolactone) Scaffolds With Bicontinuous Morphology, Society for Biomaterials 30th Annual Meeting and Exposition , Memphis, TN, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=854041 (Accessed October 10, 2025)