Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

3d, Quantitative Image Analysis Of Poly(ε-caprolactone) Scaffolds With Bicontinuous Morphology

Published

Author(s)

Joy P. Dunkers, Forrest A. Landis, K Niihara, Hiropshi Jinai

Abstract

It has been shown that scaffold microstructure impacts cell response.1 Determining the relationship between scaffold structure and cellular response facilitates scaffold design. Some descriptors of scaffold morphology thought to be influential are pore volume, pore size distribution, connectivity, curvature, and surface area. In this work, we apply methods developed for 3-dimensional (3D) characterization of polymer blends2 as bicontinuous structures to elucidate microstructural descriptors for a similarly derived poly(ε-caprolactone) (PCL) scaffold. The results here will include pore volume, pore size distribution, and connectivity. Surface curvature, surface area and anisotropy will be discussed in future work.
Conference Dates
April 27-30, 2004
Conference Location
Memphis, TN
Conference Title
Society for Biomaterials
30th Annual Meeting and Exposition

Keywords

scaffolds, pore size distribution, connectivity, curvature, poly(e-caprolactone)

Citation

Dunkers, J. , Landis, F. , Niihara, K. and Jinai, H. (2004), 3d, Quantitative Image Analysis Of Poly(ε-caprolactone) Scaffolds With Bicontinuous Morphology, Society for Biomaterials 30th Annual Meeting and Exposition , Memphis, TN, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=854041 (Accessed June 23, 2024)

Issues

If you have any questions about this publication or are having problems accessing it, please contact reflib@nist.gov.

Created April 27, 2004, Updated February 19, 2017