Pedatsur Neta

Publications

Collision-Induced Dissociation of Deprotonated Peptides. Relative Abundance of Side-Chain Neutral Losses, Residue-Specific Product Ions, and Comparison with Protonated Peptides

November 15, 2017

Author(s):

Yuxue Liang, Pedatsur Neta, Xiaoyu Yang, Stephen E. Stein

High-accuracy MS/MS spectra of deprotonated ions of 390 dipeptides and 137 peptides with 3 to 6 residues are studied. Many amino acid residues undergo neutral...

Extending A Tandem Mass Spectral Library to Include MS2 Spectra of Fragment Ions Produced In-Source and MSn Spectra

July 18, 2017

Author(s):

Xiaoyu Yang, Pedatsur Neta, Stephen E. Stein

Tandem mass spectral library searching is finding increased use as an effective means of determining chemical identity in mass spectrometry-based omics studies...

Interconversion of Peptide Mass Spectral Libraries Derivatized with iTRAQ or TMT Labels

July 07, 2016

Author(s):

Zheng Zhang, Xiaoyu Yang, Yuri A. Mirokhin, Dmitrii V. Tchekhovskoi, Weihua Ji, Sanford P. Markey, Pedatsur Neta, Bowen A. Michael, Stephen E. Stein

Derivatizing peptides with isobaric tags such as iTRAQ and TMT is widely employed in proteomics due to their ability to multiplex quantitative measurements. We...

Reaction of Arylium Ions with the Collision Gas N2 in Electrospray Ionization Mass Spectrometry

January 09, 2015

Author(s):

Yuxue Liang, Pedatsur Neta, Yamil Simon, Stephen E. Stein

RATIONALE: Tandem mass spectra of many compounds contained peaks which could not arise from the precursor ion and were different in different instruments. Such...

Unexpected Peaks in Tandem Mass Spectra due to Reaction of Product Ions with Water in Mass Spectrometer Collision Cells

December 15, 2014

Author(s):

Pedatsur Neta, Mahnaz Farahani, Yamil Simon, Yuxue Liang, Xiaoyu Yang, Stephen E. Stein

While determining the fragmentation pathways of positive ions of drugs, pesticides, metabolites, and other compounds, using electrospray ionization mass...