Kyle Anderson (Fed)

Kyle Anderson is a NIST Research Chemist and Project Leader for HDX-MS for Biopharmaceutical Analysis and also an Associate Research Professor at the University of Maryland Institute for Bioscience and Biotechnology Research (IBBR). In addition to using hydrogen/deuterium exchange mass spectrometry (HDX-MS) to characterize the structural dynamics of biopharmaceuticals, he is active in developing and promoting adoption of state-of-the-art methods for HDX-MS to ensure quality and accelerate development of biotherapeutics and biosimilars. He received the U.S. Department of Commerce Silver Medal in 2021 and Bronze Medal in 2023. He is a member of the International Society of HDX-MS, the Editorial Advisory Board for the Journal of the American Society for Mass Spectrometry, the American Society for Mass Spectrometry, and the CCQM Protein Analysis Working Group.

H/D exchange mass spectrometry (HDX-MS) for biopharmaceutical analysis

Postdoctoral Research Opportunities

National Research Council Postdoctoral Research Associate Program at NIST: Rolling application deadlines are Feb 1 and Aug 1. US citizens only. $74,950 (2022) annual salary plus benefits. Contact Kyle Anderson before applying. View Job Posting

Positions for non-US citizens: Contact Kyle Anderson directly.

Research Objectives:

• Characterize protein-based vaccines in formulation by HDX-MS
• Characterize drug-protein interactions by HDX-MS
• Adopt internal H/D exchange reporters and materials for NIST standard reference materials to improve reproducibility and harmonization of HDX-MS
• Develop HDX-MS for assessments of dynamical comparability among innovator and candidate biosimilar drugs
• Improve HDX-MS technology

2021 U.S. Department of Commerce Silver Medal
2023 U.S. Department of Commerce Bronze Medal
2019 NIST MML Outreach Accolade
2015 National Research Council Postdoctoral Research Associateship