Dmitrii V. Tchekhovskoi

Publications

Representing and Comparing Site-Specific Glycan Abundance Distributions of Glycoproteins

July 30, 2021

Author(s)

Concepcion Remoroza, Meghan Burke, Yi Liu, Yuri Mirokhin, Dmitrii Tchekhovskoi, Xiaoyu Yang, Stephen Stein

A method for representing and comparing distributions of N-linked glycans located at specific sites in proteins is presented. The representation takes the form

MS_Piano: A Software Tool for Annotating Peaks in CID Tandem Mass Spectra of Peptides and N-Glycopeptides

July 15, 2021

Author(s)

Xiaoyu Yang, Pedatsur Neta, Yuri Mirokhin, Dmitrii Tchekhovskoi, Concepcion Remoroza, Meghan Burke, Yuxue Liang, Sanford Markey, Stephen Stein

Annotating product ion peaks in tandem mass spectra is essential for evaluating spectral quality and validating peptide identification. This task is more

Sensitive Method for the Confident Identification of Genetically Variant Peptides in Human Hair

October 31, 2019

Author(s)

Zheng Zhang, Meghan Burke, William E. Wallace, Yuxue Liang, Sergey L. Sheetlin, Yuri Mirokhin, Dmitrii Tchekhovskoi, Stephen Stein

Recent reports have demonstrated that genetically variant peptides (GVPs) derived from human hair shaft proteins can be used to differentiate individuals of

Hybrid search: a method for identifying metabolites absent from tandem mass spectrometry libraries

October 10, 2019

Author(s)

Brian T. Cooper, Xinjian Yan, Yamil Simon, Dmitrii V. Tchekhovskoi, Yuri A. Mirokhin, Stephen E. Stein

Metabolomics has a critical need for better tools for mass spectral identification. Common metabolites may be identified by searching libraries of tandem mass

False Discovery Rate Estimation for Hybrid Mass Spectral Library Search Identifications in Bottom-up Proteomics

July 31, 2019

Author(s)

Meghan C. Burke, Zheng Zhang, Yuri A. Mirokhin, Dmitrii V. Tchekhovskoi, Yuxue Liang, Stephen E. Stein

We present a method for FDR estimation of mass spectral library search identifications made by a recently developed method for peptide identification, the

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Dmitrii V. Tchekhovskoi (Fed)

Publications