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Andrew Madison

Andrew C. Madison is a National Research Council Postdoctoral Research Associate in the Microsystems and Nanotechnology Division. He received a dual B.S. degree in Chemistry and Biology and a M.S. degree in Engineering Physics, both from Appalachian State University. He received a Ph.D. in Electrical and Computer Engineering from Duke University. At Duke, he developed fabrication methods for integrating acoustic, magnetic, and electrostatic devices into digital microfluidics systems. These systems use the electrowetting effect to manipulate nanoliter-scale droplets on arrays of programmable electrodes to enable laboratory-on-chip applications such as DNA sequencing, pathogen detection by quantitative polymerase chain reaction, and microbial genome engineering. He works with Samuel M. Stavis to develop fabrication and measurement methods for optical and nanofluidic devices that aim to overcome a variety of scientific challenges, ranging from the calibration of optical microscopes for super-resolution optical microscopy to multimodal characterization of colloidal nanoparticles.

Selected Publications

Piezo-driven acoustic streaming in an electrowetting-on-dielectric digital microfluidics device, A. C. Madison, M. W. Royal, R. B. Fair, Microfluidics and Nanofluidics 21, 12, 176 (2017). https://doi.org/10.1007/s10404-017-2012-6

Scalable device for automated microbial electroporation in a digital microfluidic platform. A. C. Madison, M. W. Royal, F. Vigneault, L. Chen, P. B. Griffin, M. Horowitz, G. M. Church, R. B. Fair, 
ACS Synthetic Biology 6, 9, 1701-1709 (2017). https://doi.org/10.1021/acssynbio.7b00007

Fluid transport in partially shielded electrowetting on dielectric digital microfluidic devices, A. C Madison, M. W. Royal, R. B. Fair, Journal of Microelectromechanical Systems 25, 4, 593-605 (2016). https://doi.org/10.1109/JMEMS.2016.2561699

Picoliter DNA sequencing chemistry on an electrowetting‐based digital microfluidic platform, E. R. F. Welch, Y. Y. Lin, A. C. Madison, R. B. Fair, Biotechnology Journal 6, 2, 165-176 (2011). https://doi.org/10.1002/biot.201000324

Created July 30, 2019, Updated June 9, 2020