Alexander Grishaev

Publications

High-Resolution Structural Characterization of Biomacromolecules in Aqueous Solutions from Extended q-range X-ray Scattering Data

January 16, 2023

Author(s)

Igor Levin, Alexander Grishaev, Fan Zhang, Jiahui Chen, Uta Ruett, Olaf Borkiewicz, Mrenal Bera

A Round-Robin Approach Provides a Detailed Assessment of Biomolecular Small-Angle Scattering Data Reproducibility and Yields Consensus Curves for Benchmarking.

November 1, 2022

Author(s)

Jill Trewhella, Patrice Vachette, Jan Bierma, Clement Blanchet, Emre Brookes, Srinivas Chakravarthy, Leonie Chatzimagas, Thomas Cleveland, Nathan Cowieson, Ben Crossett, Anthony P. Duff, Daniel Franke, Frank Gabel, Richard E. Gillilan, Melissa Graewert, Alexander Grishaev, Jules M. Guss, Michal Hammel, Jesse Hopkins, Qingqui Huang, Jochen S. Hub, Gregory L. Hura, Thomas C. Irving, Cy M. Jeffries, Cheol Jeong, Nigel Kirby, Susan N. Krueger, Anne Martel, Tsutomu Matsui, Na Li, Javier Perez, Lionel Porcar, Thierry Prange, Ivan Rajkovic, Mattia Rocco, Daniel J. Rosenberg, Timothy M. Ryan, Soenke Seifert, Hiroshi Sekiguchi, Dmitri Svergun, Susana C. Marujo Teixeira, Aurelien Thureau, Thomas M. Weiss, Andrew Whitten, Kathleen Wood, Xiaobing Zuo

Small-Angle Scattering (SAS) data from 5 candidate proteins (RNaseA, lysozyme, xylanase, urate oxidase and xylose isomerase) were measured on 12 Small-Angle X

Structural and Biophysical Properties of Farnesylated KRas Interacting with the Chaperone SmgGDS-558

October 4, 2022

Author(s)

Dennis J. Michalak, Bethany Unger, Ellen Lorimer, Alexander Grishaev, Carol Williams, Frank N. Heinrich, Mathias Losche

KRas is a small GTPase and membrane-bound signaling protein. Newly synthesized KRas is posttranslationally modified with a membrane-anchoring prenyl group. KRas

Conformational heterogeneity of UCAAUC RNA oligonucleotide from molecular dynamics simulations, SAXS and NMR experiments

April 28, 2022

Author(s)

Christina Bergonzo, Alexander Grishaev, Sandro Bottaro

We describe the conformational ensemble of the single-stranded r(UCAAUC) oligonucleotide obtained using extensive molecular dynamics (MD) simulations. The

Ionization and Structural Properties of mRNA Lipid Nanoparticles that Influence Expression in Intramuscular and Intravascular Administration

August 11, 2021

Author(s)

Manuel Carrasco, Suman Alishetty, Mohamad-Gabriel Alameh, Hooda Said, Lacey Wright, Mikell Paige, Ousamah Soliman, Drew Weissman, Thomas Cleveland, Alexander Grishaev, Michael Buschmann

Lipid Nanoparticles (LNPs) are used to deliver siRNA and COVID-19 mRNA vaccines. The main factor known to determine their delivery efficiency is the pKa of the

View more Publications

Alexander Grishaev (Fed)

Publications