Knowledge Integration for Bio-Threat Response

Published

September 1, 2005

Author(s)

K Verspoor, O Bodenreider, P Karp, H Kelly, S Loranger, M Musen, Ram D. Sriram, C Wroe, C Joslyn, J Ambrosiano

Abstract

Bio-threats require rapid analysis and response to prevent widespread consequences to the population. The inability to easily link and exploit biological knowledge for both human and automated analysis is a major limitation on the speed of complex knowledge development and bio-threat response. Today, linkage among the vast array of biological knowledge repositories is primarily by hand. Key requirements for smooth linkage of knowledge sources include shared ontologies of concepts and semantic relations, capabilities for unifying terminology and extracting meaningful relations from text, and inference mechanisms to link and unify heterogeneous databases. While research in all these areas continues, the gaps to the needed knowledge integration technologies are immense, and would benefit from co-ordinated cross-agency funding.

Proceedings Title

Los Alamos Technical Report, LA-UR-05-0907

Conference Location

, USA

Pub Type

Conferences

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Keywords

automated analysis, bio-threat, bio-threat response, biological knowledge, knowledge integration

Citation

Verspoor, K. , Bodenreider, O. , Karp, P. , Kelly, H. , Loranger, S. , Musen, M. , Sriram, R. , Wroe, C. , Joslyn, C. and Ambrosiano, J. (2005), Knowledge Integration for Bio-Threat Response, Los Alamos Technical Report, LA-UR-05-0907, , USA, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=822314 (Accessed October 24, 2025)