NOTICE: Due to a lapse in annual appropriations, most of this website is not being updated. Learn more.
Form submissions will still be accepted but will not receive responses at this time. Sections of this site for programs using non-appropriated funds (such as NVLAP) or those that are excepted from the shutdown (such as CHIPS and NVD) will continue to be updated.
An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
DEVELOPING METROLOGY FOR TISSUE ENGINEERING: COLLINEAR OPTICAL COHERENCE AND CONFOCAL FLUORESCENCE MICROSCOPIES
Published
Author(s)
Joy P. Dunkers, Marcus T. Cicerone, James Cooper, Forrest A. Landis, N Washburn
Abstract
We present a novel application of optical coherence microscopy (OCM) by combining it with confocal fluorescence microscopy (CFM) to gather simultaneous structural and functional information on tissue engineered medical products (TEMPs) in a registered fashion. In this work, we describe the collinear OCM and CFM instrument. We demonstrate the utility of this dual-mode technique for TEMPs by comparing the images of fluorescently stained osteoblasts cultured in a polymeric TEMP for 21 days and 10 weeks.
Proceedings Title
Proceedings of the IEEE International Symposium on Biomedical Imaging
Dunkers, J.
, Cicerone, M.
, Cooper, J.
, Landis, F.
and Washburn, N.
(2004),
DEVELOPING METROLOGY FOR TISSUE ENGINEERING: COLLINEAR OPTICAL COHERENCE AND CONFOCAL FLUORESCENCE MICROSCOPIES, Proceedings of the IEEE International Symposium on Biomedical Imaging, Arlington, VA, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=854037
(Accessed October 10, 2025)