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Combinatorial Methods to Access Cellular Response to Bis-GMA/TEGDMA Vinyl Conversion Levels
Published
Author(s)
Nancy J. Lin, L A. Bailey, N Washburn
Abstract
To facilitate the evaluation of dental composites, high throughput methods to fabricate dental resins with varying conversion levels were developed. Resins of 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy) phenyl]propane (Bis-GMA) and triethylene glycol dimethacrylate (TEGDMA) were fabricated to contain one-dimensional gradients in carbon-carbon double bond conversion. Final conversion profiles ranged from 46 % to 67 % conversion. Cellular viability was evaluated as a function of resin conversion, with viability decreasing as conversion decreased. This high-throughput method for developing samples with conversion gradients could be applied to other dental resins or photopolymerized materials.
Proceedings Title
Proceedings of the Society for Biomaterials 2005 Annual Meeting
Lin, N.
, Bailey, L.
and Washburn, N.
(2005),
Combinatorial Methods to Access Cellular Response to Bis-GMA/TEGDMA Vinyl Conversion Levels, Proceedings of the Society for Biomaterials 2005 Annual Meeting, Memphis, TN, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=852433
(Accessed October 15, 2025)