NOTICE: Due to a lapse in annual appropriations, most of this website is not being updated. Learn more.

Form submissions will still be accepted but will not receive responses at this time. Sections of this site for programs using non-appropriated funds (such as NVLAP) or those that are excepted from the shutdown (such as CHIPS and NVD) will continue to be updated.

U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PUBLICATIONS

Surfaces of Fluorinated Pyridinium Block-Copolymers with Enhanced Antibacterial Activity

Published

Author(s)

Sitaraman Krishnan, R J. Ward, A Hexemer, K E. Sohn, K L. Lee, E R. Angert, Daniel A. Fischer, E J. Kramer, Christopher K. Ober

Abstract

Polystyrene-block-poly(4-vinylpyridine) copolymers were quaternized with 1-bromohexane and 6-perfluorooctyl-1-bromohexane. Surfaces prepared from these polymers were characterized by contact angle measurements, near-edge X-ray absorption fine structure (NEXAFS) spectroscopy and X-ray photoelectron spectroscopy (XPS). The fluorinated pyridinium surfaces showed enhanced antibacterial activity compared to their non-fluorinated counterparts. Even a polymer with a relatively low molecular weight pyridinium block showed high antimicrobial activity. The bactericidal effect was found to be related to the molecular composition and organization in the top 2-3 nm of the surface, and increased with increasing hydrophilicity and pyridinium concentration of the surface.
Citation
Langmuir
Volume
22
Pub Type
Journals

Keywords

antibacterial polymers, bactericidal surfaces, fluorinated block polymers, NEXAFS, polymers, pyridinium, XPS
Ceramics and Biomaterials

Citation

Krishnan, S. , Ward, R. , Hexemer, A. , Sohn, K. , Lee, K. , Angert, E. , Fischer, D. , Kramer, E. and Ober, C. (2006), Surfaces of Fluorinated Pyridinium Block-Copolymers with Enhanced Antibacterial Activity, Langmuir (Accessed October 10, 2025)

Issues

If you have any questions about this publication or are having problems accessing it, please contact [email protected].

Created January 18, 2006, Updated October 12, 2021
Was this page helpful?