Thin Films Mechanics of Degradable Tyrosine-Derived Polycarbonate Biomaterials and Their Blends

Published

April 28, 2009

Author(s)

Khaled A. Aamer, Christopher Stafford, Lee J. Richter, J Kohn, Matthew Becker

Abstract

The integrity, function, and performance of biomedical devices possessing thin polymeric coatings are critically dependent on the thin film mechanical properties, including the elastic modulus. In this report, the elastic moduli of several tyrosine-derived polycarbonates, specifically desaminotyrosyl ethyl tyrosine polycarbonates p(DTE)c, an iodinated derivative p(I2-DTE)c, and several discrete blends are measured by using strain-induced elastic buckling instability for mechanical measurements (SIEBIMM) method. The data collected on the blends show that the elastic modulus is statistically independent on the blend composition as the weight percentage of p(I2-DTE)c increases for films of uniform thickness in the ranges 67 nm to 100 nm and 150 to 200 nm. The observed elastic moduli of p(DTE)c increases with decreasing film thickness in the range of 80-160 nm and plateau in the range 80 to 30 nm. The stiffening of the thin film is consistent with the confinement effect of thickness on the polymers elastic moduli for polycarbonates.

Citation

Advanced Materials

Pub Type

Journals

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Keywords

tyrosine-derived polycarbonates, buckling instability, elastic modulus, SIEBIMM, confinement

Citation

Aamer, K. , Stafford, C. , Richter, L. , Kohn, J. and Becker, M. (2009), Thin Films Mechanics of Degradable Tyrosine-Derived Polycarbonate Biomaterials and Their Blends, Advanced Materials, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=854035 (Accessed October 10, 2025)