U.S. domestic cats as sentinels for perfluoroalkyl substances: Possible linkages with housing, obesity, and disease

Published

August 2, 2016

Author(s)

Jessica L. Reiner, Andrew B. Lindstrom, Phillip C. Bost, Janice Dye, Jerry Zweigenbaum, Mark J. Strynar

Abstract

Perfluoroalkyl substances (PFAS), such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), are persistent, globally distributed, anthropogenic compounds. The primary source(s) for human exposure are not well understood although within home exposure is likely important since many consumer products have been treated with different PFAS, and people spend much of their lives indoors. Herein, domestic cats were used as sentinels to investigate potential exposure and health linkages. PFAS in serum samples of 72 pet and feral cats, including 11 healthy and 61 with one or more primary disease diagnoses, were quantitated using high-resolution time-of-flight mass spectroscopy. All but one sample had detectable PFAS, with PFOS and perfluorohexane sulfonate (PFHxS) ranging from

Citation

Environmental Research

Issue

151

Pub Type

Journals

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DOI Link

Keywords

Cats, Obesity, Perfluoroalkyl substances (PFAS), Sentinels

Citation

Reiner, J. , Lindstrom, A. , Bost, P. , Dye, J. , Zweigenbaum, J. and Strynar, M. (2016), U.S. domestic cats as sentinels for perfluoroalkyl substances: Possible linkages with housing, obesity, and disease, Environmental Research, [online], https://doi.org/10.1016/j.envres.2016.07.027 (Accessed October 8, 2025)