The authors investigate the extent to which the RESPONSE Evaluation Criateria in Solid Tumors (RECIST) can predict tumor volumes and changes in volume using clinical data. The data presented are a reanalysis of data acquired in other studies, including the public database from the Lung Image Database Consortium (LID) and from a study of liver malignoma. The principal conclusion is that a given RECIST diameter predicts volume to a factor of 17 or 10 respectively with 95 % confidence and that changes in volume are predicted only a little better: to within a factor of 8 for the liver data. Additionally, we show the RECIST threshold of 10 mm to follow a nodule corresponds to a transition zone of a factor fo 10 in volume for the nodules in the LIDC database.
Citation: Medical Physics
Pub Type: Journals
RECIST , LIDC , nodule , volumetrics