Pease, L.
, Feldblyum, J.
, DePaoli Lacaerda, S.
, Anumolu, R.
, Yim, P.
, Clarke, M.
, Kang, H.
and Hwang, J.
(2010),
Structural Analysis of Soft Multicomponent Nanoparticle Clusters Using Electrospray Differential Mobility Analysis with Transmission Electron Microscopy, Nano Letters
(Accessed October 16, 2025)
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Structural Analysis of Soft Multicomponent Nanoparticle Clusters Using Electrospray Differential Mobility Analysis with Transmission Electron Microscopy
Published
Author(s)
Leonard F. Pease , Jeremy Feldblyum, Silvia H. DePaoli Lacaerda, Rajesekhar Anumolu, , , ,
Abstract
Rapid and quantitative techniques are essential to analyze soft multicomponent nanoparticle clusters. Here we combine electrospray differential mobility analysis (ES-DMA), which measures the size of the entire cluster, with transmission electron microscopy (TEM), which detects the hard components, to determine the presence and composition of the softer components. Results demonstrate the power of the combined analysis to quantify the composition of soft coronas on nanoparticles and the number of quantum dots attached to lambda phage.Citation
Nano Letters
Volume
4
Issue
11
Pub Type
Journals
Keywords
composite nanoparticles, electrospray differential mobility analysis, quantum dot, virus, phage, streptavidin.
Citation
Issues
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Created October 21, 2010, Updated October 12, 2021