Measurement of the optical properties of solid biomedical phantoms at the National Institute of Standards and Technology

Published

March 6, 2015

Author(s)

Paul Lemaillet, David W. Allen, Jeeseong C. Hwang

Abstract

Solid phantoms that serve as a proxy for human tissue and provide a convenient test subject for optical medical imaging devices. In order to determine quantitative performance of a given system, the absolute optical properties of the subject must be known. Currently there is no national scale applicable to the scattering and absorption properties of solid diffuse tissue phantoms that would provide traceability and estimated measurement uncertainties. This paper describe progress in the development of a facility dedicated to the determination of the optical properties of solid biomedical phantoms. A brief description of the system, data analysis, Graphical User Interface (GUI), and the uncertainties is provided. The design is based on a double-integrating sphere steady state domain approach. The initial evaluation of the system includes the measurement of solid phantoms and a comparison to the manufactures' values that were determined by a time resolved approach. The initial results indicate that the agreement is within the estimated uncertainties with the coverage factor k=2.

Citation

SPIE Conference Proceedings

Volume

9325

Pub Type

Journals

Download Paper

https://doi.org/10.1117/12.2085110

Local Download

Keywords

solid biomedical phantoms, double-integrating spheres, adding doubling, uncertainty budget

Citation

Lemaillet, P. , Allen, D. and Hwang, J. (2015), Measurement of the optical properties of solid biomedical phantoms at the National Institute of Standards and Technology, SPIE Conference Proceedings, [online], https://doi.org/10.1117/12.2085110, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=917965 (Accessed October 9, 2025)