Rezaei, S.
, Blick, E.
, Mineart, K.
and Kelley, E.
(2025),
Linking Chemical Degradation and Physical Instability of Lipid Vesicles, Academic Press, London, , [online], https://doi.org/10.1016/bs.abl.2025.05.001, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=959820
(Accessed October 8, 2025)
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Linking Chemical Degradation and Physical Instability of Lipid Vesicles
Published
Author(s)
Sharareh Rezaei, Emily Blick, Kenneth Mineart,
Abstract
Lipid vesicles are applicable in a wide variety of uses including both academic and commercial avenues. In all of these cases, it is crucial to understand and connect the chemical degradation of constituent molecules – i.e., lipids – with the physical instability of the vesicles since their function can be greatly altered if compromised. This chapter offers a concise overview of the two main pathways through which lipid molecules chemically degrade – oxidation and hydrolysis. Next, it highlights factors that lead to physical instability of lipid vesicles. Within each section, relevant analytical techniques are included. We conclude by presenting preliminary data that highlights our recent efforts to relate lipid chemical degradation and vesicle instability.Citation
Advances in Biomembranes and Lipid Self-Assembly
Volume
41
Publisher Info
Academic Press, London,
Pub Type
Books
Download Paper
Keywords
lipid, chemical stability, physical stability, degradation, oxidation, hydrolysis, lysolipid, vesicle, liposome
Citation
Issues
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Created January 1, 2025, Updated July 21, 2025