2023 Judson C. French Award

The team is recognized for development and extensive characterization of an SRM comprised of N-linked glycans (branched sugar chains) that are critical to the quality and safety of monoclonal antibody (mAb) protein therapeutics. This SRM is the world's first SI-traceable, quantitative standard for glycans and was developed through collaboration with stakeholders in the biopharmaceutical industry, the glycomics field, and academia. Characterization of the SRM required development of novel mass spectrometry-based techniques and other techniques to measure the quantity and purity of 13 unique but structurally similar glycans. This new SRM provides a foundation for benchmarking and validating glycan measurements in the biopharmaceutical industry.