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Using strands of DNA to create miniature hinges that pop open or shut when binding to specific molecules, researchers at the National Institute of Standards and
Nearly every modern cellphone has a built-in compass, or magnetometer, that detects the direction of Earth’s magnetic field, providing critical information for
Technology Transfer is an intensely dynamic field, and the process of moving federal scientific and technological research from the lab to the marketplace teems
Electromagnetic devices cannot operate without the interaction of electromagnetic waves with materials, and the characterization of the interface between fields and materials will be a critical task for any device or metrology development from nanoscale to larger scales. Areas of impact over the
In many cases, SEM measurements are carried out without knowledge of the best measurement conditions, partly due to engineering limits of the SEM, but also due to lack of thorough knowledge of the physics of the signal generation. For example, in many cases the best-quality results can be obtained
This project aims to develop light-scattering microscopy methods for rapid, multi-attribute characterization of gene therapy particles at the single particle level. Emerging gene therapy treatments use gene delivery particles, such as viral vectors and non-viral carriers, to cure intractable
Minimal cells are cells whose genome has been stripped of all but those genes essential for replication, in a process called "genome minimization." NIST and collaborators demonstrated genome minimization coupled to single cell imaging as a powerful approach to investigate the minimal genetic
Yechan Noh, Demian Riccardi, Alexander Smolyanitsky
Aqueous cations permeate subnanoscale pores by crossing free energy barriers dominated by competing enthalpic contributions from transiently decreased ion
Yuhao Li, Sidi Zhao, Rahul Prasanna Misra, Chenxing Liang, Alice Judith Gillen, jobaer abdullah, Ted Laurence, Jeffrey Fagan, Narayana Aluru, Daniel Blankschtein, Aleksandr Noy
Nanofluidic channels impose extreme confinement on water and ions, giving rise to unusual transport phenomena that strongly depend on the interactions at the
Nicholas Drachman, Paul Patrone, Gregory A. Cooksey
Accuracy and temporal resolution of flow meters are often unacceptable below the microliter per minute scale, limiting their ability to evaluate the real-time