Nanofluidics

News and Updates

Identifying Individual Molecules: NIST Study Suggests How to Build a Better ‘Nanopore’ Biosensor

April 27, 2021

Researchers have spent more than three decades developing and studying miniature biosensors that can identify single molecules. In five to 10 years, when such

NIST Goes With the (Slow) Flow: New Technique Could Improve Biotech, Precision Medicine

September 26, 2019

Researchers at the National Institute of Standards and Technology (NIST) have developed an optical system that accurately measures the flow of extraordinarily

Horizontal blue mesh shaped like chicken wire featuring a regular pattern of some bigger holes. White balls are scattered around and some are going through the big holes.

NIST Simulations Suggest Graphene Can Stretch to Be a Tunable Ion Filter

November 26, 2018

Researchers at the National Institute of Standards and Technology (NIST) have conducted simulations suggesting that graphene, in addition to its many other

Projects and Programs

zCompleted - Micro-rheometry

Our goal is to develop and promote the adoption of small-volume rheological methods for complex fluids including bio-fluids, suspensions and polymers, where

Computational Scanning Electron Microscopy

To advance the development of nanometer-scale devices and systems, there is a need to image and characterize nanostructured materials very precisely and

Nanoparticle Tracking for Fluidic Self Assembly (Archived)

One challenge of nanomanufacturing is to establish methods to assemble solution-based nanoparticles into organized structures with nanometer precision, with an

Manipulating the Position and Orientation of Nanoparticles using Feedback Control (Archived)

To advance the development of miniaturized systems, there is a need to place nanostructured materials in very precise locations. Only then can practical

Publications

Laser-based temperature control to study the roles of entropy and enthalpy in polymer-nanopore interactions

April 21, 2021

Author(s)

Christopher Angevine, Joseph W. Robertson, Amala Dass, Joseph E. Reiner

Probing Electrified Liquid-Solid Interfaces with Scanning Electron Microscopy

December 2, 2020

Author(s)

Hongxuan Guo, Alexander Yulaev, Evgheni Strelcov, Alexander Tselev, Christopher M. Arble, Andras Vladar, John S. Villarrubia, Andrei A. Kolmakov

The mean free path of secondary electrons in aqueous solutions is on the order of a nanometer, making them a suitable probe of ultrathin electrical double

Diffusion limitations and translocation barriers in atomically thin biomimetic pores

November 20, 2020

Author(s)

Subin Sahu, Michael P. Zwolak

Ionic transport in nano- to subnano-scale pores is highly dependent on translocation barriers and potential wells. These features in the free-energy landscape

Dynamic Measurement of Nanoflows: Realization of an Optofluidic Flow Meter to the Nanoliter-per- Minute Scale

August 8, 2019

Author(s)

Gregory A. Cooksey, Paul N. Patrone, James R. Hands, Stephen E. Meek, Anthony J. Kearsley

The ultimate performance of flow-based measurements in microfluidic systems is limited by their accuracy at the nanoliter-per-minute scale. But improving such